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Seasonality and ambient temperature at time of conception in term-born individuals – influences on cardiovascular disease and obesity in adult life

BACKGROUND: The influence of environmental conditions early in life – including temperature and season – on health later in life has so far not attracted much attention. OBJECTIVE: Using data from the Helsinki Birth Cohort Study of 13,345 men and women, the influence of temperature and season at mon...

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Autores principales: Schreier, Nadja, Moltchanova, Elena, Forsén, Tom, Kajantie, Eero, Eriksson, Johan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Co-Action Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797918/
https://www.ncbi.nlm.nih.gov/pubmed/24137570
http://dx.doi.org/10.3402/ijch.v72i0.21466
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author Schreier, Nadja
Moltchanova, Elena
Forsén, Tom
Kajantie, Eero
Eriksson, Johan G.
author_facet Schreier, Nadja
Moltchanova, Elena
Forsén, Tom
Kajantie, Eero
Eriksson, Johan G.
author_sort Schreier, Nadja
collection PubMed
description BACKGROUND: The influence of environmental conditions early in life – including temperature and season – on health later in life has so far not attracted much attention. OBJECTIVE: Using data from the Helsinki Birth Cohort Study of 13,345 men and women, the influence of temperature and season at month of conception on birth weight, and on cardiovascular diseases and obesity-related traits in later life was studied. DESIGN: Linear regressions were fitted to examine the relationship between birth weight/obesity-related variables/hypertension and alternatively month of conception and average temperature of month of conception. The incidence of both coronary heart disease and cerebrovascular disease was assumed to follow a Weibull hazard model, and was modelled accordingly using survival analysis techniques. RESULTS: In women, unusually cold temperatures at month of conception predicted lower body mass index (BMI) and fat percentage, and protected from obesity. Warmer temperatures at month of conception were associated with higher risk for hypertension. In men, warmer temperatures around conception predicted lower BMI. No seasonal influences were detected on obesity-related variables, nor were there seasonal or temperature mediated influences on birth weight, coronary heart disease or cerebrovascular disease observed. CONCLUSIONS: We suggest that ambient temperature has an influence on obesity-related outcomes and hypertension. This merits further study, also with regard to other health outcomes and from a global perspective.
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spelling pubmed-37979182013-10-17 Seasonality and ambient temperature at time of conception in term-born individuals – influences on cardiovascular disease and obesity in adult life Schreier, Nadja Moltchanova, Elena Forsén, Tom Kajantie, Eero Eriksson, Johan G. Int J Circumpolar Health Original Research Article BACKGROUND: The influence of environmental conditions early in life – including temperature and season – on health later in life has so far not attracted much attention. OBJECTIVE: Using data from the Helsinki Birth Cohort Study of 13,345 men and women, the influence of temperature and season at month of conception on birth weight, and on cardiovascular diseases and obesity-related traits in later life was studied. DESIGN: Linear regressions were fitted to examine the relationship between birth weight/obesity-related variables/hypertension and alternatively month of conception and average temperature of month of conception. The incidence of both coronary heart disease and cerebrovascular disease was assumed to follow a Weibull hazard model, and was modelled accordingly using survival analysis techniques. RESULTS: In women, unusually cold temperatures at month of conception predicted lower body mass index (BMI) and fat percentage, and protected from obesity. Warmer temperatures at month of conception were associated with higher risk for hypertension. In men, warmer temperatures around conception predicted lower BMI. No seasonal influences were detected on obesity-related variables, nor were there seasonal or temperature mediated influences on birth weight, coronary heart disease or cerebrovascular disease observed. CONCLUSIONS: We suggest that ambient temperature has an influence on obesity-related outcomes and hypertension. This merits further study, also with regard to other health outcomes and from a global perspective. Co-Action Publishing 2013-10-15 /pmc/articles/PMC3797918/ /pubmed/24137570 http://dx.doi.org/10.3402/ijch.v72i0.21466 Text en © 2013 Nadja Schreier et al. http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research Article
Schreier, Nadja
Moltchanova, Elena
Forsén, Tom
Kajantie, Eero
Eriksson, Johan G.
Seasonality and ambient temperature at time of conception in term-born individuals – influences on cardiovascular disease and obesity in adult life
title Seasonality and ambient temperature at time of conception in term-born individuals – influences on cardiovascular disease and obesity in adult life
title_full Seasonality and ambient temperature at time of conception in term-born individuals – influences on cardiovascular disease and obesity in adult life
title_fullStr Seasonality and ambient temperature at time of conception in term-born individuals – influences on cardiovascular disease and obesity in adult life
title_full_unstemmed Seasonality and ambient temperature at time of conception in term-born individuals – influences on cardiovascular disease and obesity in adult life
title_short Seasonality and ambient temperature at time of conception in term-born individuals – influences on cardiovascular disease and obesity in adult life
title_sort seasonality and ambient temperature at time of conception in term-born individuals – influences on cardiovascular disease and obesity in adult life
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797918/
https://www.ncbi.nlm.nih.gov/pubmed/24137570
http://dx.doi.org/10.3402/ijch.v72i0.21466
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