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HLA-DM Focuses on Conformational Flexibility Around P1 Pocket to Catalyze Peptide Exchange
Peptides presented by major histocompatibility complex class II (MHCII) molecules to CD4+ T cells play a central role in the initiation of adaptive immunity. This antigen presentation process is characterized by the proteolytic cleavage of foreign and self proteins, and loading of the resultant pept...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797982/ https://www.ncbi.nlm.nih.gov/pubmed/24146666 http://dx.doi.org/10.3389/fimmu.2013.00336 |