Prostaglandin E(2) is critical for the development of niacin-deficiency-induced photosensitivity via ROS production

Pellagra is a photosensitivity syndrome characterized by three “D's”: diarrhea, dermatitis, and dementia as a result of niacin deficiency. However, the molecular mechanisms of photosensitivity dermatitis, the hallmark abnormality of this syndrome, remain unclear. We prepared niacin deficient mi...

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Detalles Bibliográficos
Autores principales: Sugita, Kazunari, Ikenouchi-Sugita, Atsuko, Nakayama, Yasuko, Yoshioka, Haruna, Nomura, Takashi, Sakabe, Jun-ichi, Nakahigashi, Kyoko, Kuroda, Etsushi, Uematsu, Satoshi, Nakamura, Jun, Akira, Shizuo, Nakamura, Motonobu, Narumiya, Shuh, Miyachi, Yoshiki, Tokura, Yoshiki, Kabashima, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797990/
https://www.ncbi.nlm.nih.gov/pubmed/24131900
http://dx.doi.org/10.1038/srep02973

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