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Local delivery of controlled-release simvastatin/PLGA/HAp microspheres enhances bone repair

Statins are used clinically for reduction of cholesterol synthesis to prevent cardiovascular disease. Previous in vitro and in vivo studies have shown that statins stimulate bone formation. However, orally administered statins may be degraded during first-pass metabolism in the liver. This study aim...

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Detalles Bibliográficos
Autores principales:	Tai, I-Chun, Fu, Yin-Chih, Wang, Chih-Kuang, Chang, Je-Ken, Ho, Mei-Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2013
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798145/ https://www.ncbi.nlm.nih.gov/pubmed/24143094 http://dx.doi.org/10.2147/IJN.S48694

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