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Ethanol exposure disrupts extraembryonic microtubule cytoskeleton and embryonic blastomere cell adhesion, producing epiboly and gastrulation defects
Fetal alcohol spectrum disorder (FASD) occurs when pregnant mothers consume alcohol, causing embryonic ethanol exposure and characteristic birth defects that include craniofacial, neural and cardiac defects. Gastrulation is a particularly sensitive developmental stage for teratogen exposure, and zeb...
Autores principales: | Sarmah, Swapnalee, Muralidharan, Pooja, Curtis, Courtney L., McClintick, Jeanette N., Buente, Bryce B., Holdgrafer, David J., Ogbeifun, Osato, Olorungbounmi, Opeyemi C., Patino, Liliana, Lucas, Ryan, Gilbert, Sonya, Groninger, Evan S., Arciero, Julia, Edenberg, Howard J., Marrs, James A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798184/ https://www.ncbi.nlm.nih.gov/pubmed/24167711 http://dx.doi.org/10.1242/bio.20135546 |
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