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Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin
Although ubiquitin is thought to be important for the autophagic sequestration of invading bacteria (also called xenophagy), its precise role remains largely enigmatic. Here we determined how ubiquitin is involved in this process. After invasion, ubiquitin is conjugated to host cellular proteins in...
Autores principales: | Fujita, Naonobu, Morita, Eiji, Itoh, Takashi, Tanaka, Atsushi, Nakaoka, Megumi, Osada, Yuki, Umemoto, Tetsuo, Saitoh, Tatsuya, Nakatogawa, Hitoshi, Kobayashi, Shouhei, Haraguchi, Tokuko, Guan, Jun-Lin, Iwai, Kazuhiro, Tokunaga, Fuminori, Saito, Kazunobu, Ishibashi, Koutaro, Akira, Shizuo, Fukuda, Mitsunori, Noda, Takeshi, Yoshimori, Tamotsu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798248/ https://www.ncbi.nlm.nih.gov/pubmed/24100292 http://dx.doi.org/10.1083/jcb.201304188 |
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