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Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin

Although ubiquitin is thought to be important for the autophagic sequestration of invading bacteria (also called xenophagy), its precise role remains largely enigmatic. Here we determined how ubiquitin is involved in this process. After invasion, ubiquitin is conjugated to host cellular proteins in...

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Detalles Bibliográficos
Autores principales: Fujita, Naonobu, Morita, Eiji, Itoh, Takashi, Tanaka, Atsushi, Nakaoka, Megumi, Osada, Yuki, Umemoto, Tetsuo, Saitoh, Tatsuya, Nakatogawa, Hitoshi, Kobayashi, Shouhei, Haraguchi, Tokuko, Guan, Jun-Lin, Iwai, Kazuhiro, Tokunaga, Fuminori, Saito, Kazunobu, Ishibashi, Koutaro, Akira, Shizuo, Fukuda, Mitsunori, Noda, Takeshi, Yoshimori, Tamotsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798248/
https://www.ncbi.nlm.nih.gov/pubmed/24100292
http://dx.doi.org/10.1083/jcb.201304188

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