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De Novo ORFs in Drosophila Are Important to Organismal Fitness and Evolved Rapidly from Previously Non-coding Sequences
How non-coding DNA gives rise to new protein-coding genes (de novo genes) is not well understood. Recent work has revealed the origins and functions of a few de novo genes, but common principles governing the evolution or biological roles of these genes are unknown. To better define these principles...
Autores principales: | Reinhardt, Josephine A., Wanjiru, Betty M., Brant, Alicia T., Saelao, Perot, Begun, David J., Jones, Corbin D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798262/ https://www.ncbi.nlm.nih.gov/pubmed/24146629 http://dx.doi.org/10.1371/journal.pgen.1003860 |
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