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On the Role of Aggregation Prone Regions in Protein Evolution, Stability, and Enzymatic Catalysis: Insights from Diverse Analyses

The various roles that aggregation prone regions (APRs) are capable of playing in proteins are investigated here via comprehensive analyses of multiple non-redundant datasets containing randomly generated amino acid sequences, monomeric proteins, intrinsically disordered proteins (IDPs) and catalyti...

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Detalles Bibliográficos
Autores principales: Buck, Patrick M., Kumar, Sandeep, Singh, Satish K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798281/
https://www.ncbi.nlm.nih.gov/pubmed/24146608
http://dx.doi.org/10.1371/journal.pcbi.1003291

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