M.tuberculosis Mutants Lacking Oxygenated Mycolates Show Increased Immunogenicity and Protective Efficacy as Compared to M. bovis BCG Vaccine in an Experimental Mouse Model

The existing vaccine against tuberculosis (M. bovis BCG) exerts some protection against the extrapulmonary forms of the disease, particularly in young children, but is not very effective against the pulmonary form of TB, which often results from the reactivation of a latent M. tuberculosis (M.tb)inf...

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Detalles Bibliográficos
Autores principales: Hedhli, Dorsaf, Denis, Olivier, Barkan, Daniel, Daffé, Mamadou, Glickman, Michael S., Huygen, Kris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798287/
https://www.ncbi.nlm.nih.gov/pubmed/24146869
http://dx.doi.org/10.1371/journal.pone.0076442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798287/
https://www.ncbi.nlm.nih.gov/pubmed/24146869
http://dx.doi.org/10.1371/journal.pone.0076442

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