Valproic Acid Treatment Inhibits Hypoxia-Inducible Factor 1α Accumulation and Protects against Burn-Induced Gut Barrier Dysfunction in a Rodent Model

OBJECTIVE: Burn-induced gut dysfunction plays an important role in the development of sepsis and multiple organ dysfunction. Emerging evidence suggests that hypoxia-inducible factor-1α (HIF-1α) is critical in paracelluar barrier functions via regulating vascular endothelial growth factor (VEGF) and...

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Detalles Bibliográficos
Autores principales: Luo, Hong-Min, Du, Ming-Hua, Lin, Zhi-Long, Zhang, Lin, Ma, Li, Wang, Huan, Yu, Wen, Lv, Yi, Lu, Jiang-Yang, Pi, Yu-Li, Hu, Sen, Sheng, Zhi-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798300/
https://www.ncbi.nlm.nih.gov/pubmed/24147016
http://dx.doi.org/10.1371/journal.pone.0077523

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