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American cutaneous leishmaniasis: epidemiological profile of patients treated in Londrina from 1998 to 2009()

BACKGROUND: American cutaneous leishmaniasis is a dermatozoonosis of compulsory notification with relevant morbidity. The disease is considered endemic in northern Paraná. OBJECTIVES: To evaluate the clinical, laboratory and epidemiological aspects of patients with American cutaneous leishmaniasis t...

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Autores principales: Junior, Rubens Pontello, Gon, Airton dos Santos, Ogama, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798351/
https://www.ncbi.nlm.nih.gov/pubmed/24173180
http://dx.doi.org/10.1590/abd1806-4841.20132168
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author Junior, Rubens Pontello
Gon, Airton dos Santos
Ogama, Alessandra
author_facet Junior, Rubens Pontello
Gon, Airton dos Santos
Ogama, Alessandra
author_sort Junior, Rubens Pontello
collection PubMed
description BACKGROUND: American cutaneous leishmaniasis is a dermatozoonosis of compulsory notification with relevant morbidity. The disease is considered endemic in northern Paraná. OBJECTIVES: To evaluate the clinical, laboratory and epidemiological aspects of patients with American cutaneous leishmaniasis treated at Clinics Hospital, State University of Londrina, Brazil (Paraná). METHODS: This was an observational, cross-sectional, retrospective and descriptive study. The medical records of patients with American cutaneous leishmaniasis treated at the University Hospital of Londrina - Paraná, from 1998 to 2009 were evaluated. RESULTS: A total of 470 patients, with prevalence of 8.72 cases / 100,000 inhabitants, participated in the study. Most patients were male, aged 21-40 years, with a single ulcerated lesion as the most common clinical presentation, located mainly in an exposed area of the body. With regard to immunological tests, the Montenegro intradermal reaction was positive in 84.4% of cases. Treatment with pentavalent antimony was well tolerated, and patient follow-up for a year occurred in 59% of cases. CONCLUSION: American cutaneous leishmaniasis is still an endemic disease in the region, with a high potential for morbidity, but with a cure rate of around 95% after treatment. The use of immunological techniques facilitates the diagnosis of clinically suspicious cases.
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spelling pubmed-37983512013-10-25 American cutaneous leishmaniasis: epidemiological profile of patients treated in Londrina from 1998 to 2009() Junior, Rubens Pontello Gon, Airton dos Santos Ogama, Alessandra An Bras Dermatol Investigation BACKGROUND: American cutaneous leishmaniasis is a dermatozoonosis of compulsory notification with relevant morbidity. The disease is considered endemic in northern Paraná. OBJECTIVES: To evaluate the clinical, laboratory and epidemiological aspects of patients with American cutaneous leishmaniasis treated at Clinics Hospital, State University of Londrina, Brazil (Paraná). METHODS: This was an observational, cross-sectional, retrospective and descriptive study. The medical records of patients with American cutaneous leishmaniasis treated at the University Hospital of Londrina - Paraná, from 1998 to 2009 were evaluated. RESULTS: A total of 470 patients, with prevalence of 8.72 cases / 100,000 inhabitants, participated in the study. Most patients were male, aged 21-40 years, with a single ulcerated lesion as the most common clinical presentation, located mainly in an exposed area of the body. With regard to immunological tests, the Montenegro intradermal reaction was positive in 84.4% of cases. Treatment with pentavalent antimony was well tolerated, and patient follow-up for a year occurred in 59% of cases. CONCLUSION: American cutaneous leishmaniasis is still an endemic disease in the region, with a high potential for morbidity, but with a cure rate of around 95% after treatment. The use of immunological techniques facilitates the diagnosis of clinically suspicious cases. Sociedade Brasileira de Dermatologia 2013 /pmc/articles/PMC3798351/ /pubmed/24173180 http://dx.doi.org/10.1590/abd1806-4841.20132168 Text en ©2013 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Investigation
Junior, Rubens Pontello
Gon, Airton dos Santos
Ogama, Alessandra
American cutaneous leishmaniasis: epidemiological profile of patients treated in Londrina from 1998 to 2009()
title American cutaneous leishmaniasis: epidemiological profile of patients treated in Londrina from 1998 to 2009()
title_full American cutaneous leishmaniasis: epidemiological profile of patients treated in Londrina from 1998 to 2009()
title_fullStr American cutaneous leishmaniasis: epidemiological profile of patients treated in Londrina from 1998 to 2009()
title_full_unstemmed American cutaneous leishmaniasis: epidemiological profile of patients treated in Londrina from 1998 to 2009()
title_short American cutaneous leishmaniasis: epidemiological profile of patients treated in Londrina from 1998 to 2009()
title_sort american cutaneous leishmaniasis: epidemiological profile of patients treated in londrina from 1998 to 2009()
topic Investigation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798351/
https://www.ncbi.nlm.nih.gov/pubmed/24173180
http://dx.doi.org/10.1590/abd1806-4841.20132168
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