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Signal One and Two Blockade Are Both Critical for Non-Myeloablative Murine HSCT across a Major Histocompatibility Complex Barrier

Non-myeloablative allogeneic haematopoietic stem cell transplantation (HSCT) is rarely achievable clinically, except where donor cells have selective advantages. Murine non-myeloablative conditioning regimens have limited clinical success, partly through use of clinically unachievable cell doses or...

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Detalles Bibliográficos
Autores principales:	Langford-Smith, Kia J., Sandiford, Zara, Langford-Smith, Alex, Wilkinson, Fiona L., Jones, Simon A., Wraith, J. Ed, Wynn, Robert F., Bigger, Brian W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798400/ https://www.ncbi.nlm.nih.gov/pubmed/24147041 http://dx.doi.org/10.1371/journal.pone.0077632

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