The Structure of Classical Swine Fever Virus N(pro): A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction

Pestiviruses express their genome as a single polypeptide that is subsequently cleaved into individual proteins by host- and virus-encoded proteases. The pestivirus N-terminal protease (N(pro)) is a cysteine autoprotease that cleaves between its own C-terminus and the N-terminus of the core protein....

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Detalles Bibliográficos
Autores principales: Gottipati, Keerthi, Ruggli, Nicolas, Gerber, Markus, Tratschin, Jon-Duri, Benning, Matthew, Bellamy, Henry, Choi, Kyung H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798407/
https://www.ncbi.nlm.nih.gov/pubmed/24146623
http://dx.doi.org/10.1371/journal.ppat.1003704

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