Glyburide Reduces Bacterial Dissemination in a Mouse Model of Melioidosis

BACKGROUND: Burkholderia pseudomallei infection (melioidosis) is an important cause of community-acquired Gram-negative sepsis in Northeast Thailand, where it is associated with a ∼40% mortality rate despite antimicrobial chemotherapy. We showed in a previous cohort study that patients taking glybur...

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Detalles Bibliográficos
Autores principales: Koh, Gavin C. K. W., Weehuizen, Tassili A., Breitbach, Katrin, Krause, Kathrin, de Jong, Hanna K., Kager, Liesbeth M., Hoogendijk, Arjan J., Bast, Antje, Peacock, Sharon J., van der Poll, Tom, Steinmetz, Ivo, Wiersinga, W. Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798430/
https://www.ncbi.nlm.nih.gov/pubmed/24147174
http://dx.doi.org/10.1371/journal.pntd.0002500

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