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A Structural Basis for BRD2/4-Mediated Host Chromatin Interaction and Oligomer Assembly of Kaposi Sarcoma-Associated Herpesvirus and Murine Gammaherpesvirus LANA Proteins

Kaposi sarcoma-associated herpesvirus (KSHV) establishes a lifelong latent infection and causes several malignancies in humans. Murine herpesvirus 68 (MHV-68) is a related γ(2)-herpesvirus frequently used as a model to study the biology of γ-herpesviruses in vivo. The KSHV latency-associated nuclear...

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Detalles Bibliográficos
Autores principales: Hellert, Jan, Weidner-Glunde, Magdalena, Krausze, Joern, Richter, Ulrike, Adler, Heiko, Fedorov, Roman, Pietrek, Marcel, Rückert, Jessica, Ritter, Christiane, Schulz, Thomas F., Lührs, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798688/
https://www.ncbi.nlm.nih.gov/pubmed/24146614
http://dx.doi.org/10.1371/journal.ppat.1003640