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CD28: Direct and Critical Receptor for Superantigen Toxins

Every adaptive immune response requires costimulation through the B7/CD28 axis, with CD28 on T-cells functioning as principal costimulatory receptor. Staphylococcal and streptococcal superantigen toxins hyperstimulate the T-cell-mediated immune response by orders of magnitude, inducing a lethal cyto...

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Detalles Bibliográficos
Autores principales:	Kaempfer, Raymond, Arad, Gila, Levy, Revital, Hillman, Dalia, Nasie, Iris, Rotfogel, Ziv
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798871/ https://www.ncbi.nlm.nih.gov/pubmed/24022021 http://dx.doi.org/10.3390/toxins5091531

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