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HIV-1 Infection of T Cells and Macrophages Are Differentially Modulated by Virion-Associated Hck: A Nef-Dependent Phenomenon

The proline repeat motif (PxxP) of Nef is required for interaction with the SH3 domains of macrophage-specific Src kinase Hck. However, the implication of this interaction for viral replication and infectivity in macrophages and T lymphocytes remains unclear. Experiments in HIV-1 infected macrophage...

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Detalles Bibliográficos
Autores principales:	Cornall, Alyssa, Mak, Johnson, Greenway, Alison, Tachedjian, Gilda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798898/ https://www.ncbi.nlm.nih.gov/pubmed/24051604 http://dx.doi.org/10.3390/v5092235

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