Lysyl oxidase secreted by tumour endothelial cells promotes angiogenesis and metastasis

BACKGROUND: Molecules that are highly expressed in tumour endothelial cells (TECs) may be candidates for specifically targeting TECs. Using DNA microarray analysis, we found that the lysyl oxidase (LOX) gene was upregulated in TECs compared with its expression in normal endothelial cells (NECs). LOX...

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Detalles Bibliográficos
Autores principales: Osawa, T, Ohga, N, Akiyama, K, Hida, Y, Kitayama, K, Kawamoto, T, Yamamoto, K, Maishi, N, Kondoh, M, Onodera, Y, Fujie, M, Shinohara, N, Nonomura, K, Shindoh, M, Hida, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798951/
https://www.ncbi.nlm.nih.gov/pubmed/24045659
http://dx.doi.org/10.1038/bjc.2013.535

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