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Long non-coding RNA HOTAIR, a driver of malignancy, predicts negative prognosis and exhibits oncogenic activity in oesophageal squamous cell carcinoma

BACKGROUND: HOX transcript antisense RNA (HOTAIR), which is expressed from the homebox C gene (HOXC) locus, is capable of reprogramming chromatin organisation and promoting cancer cell metastasis and can simultaneously bind the polycomb repressive complex 2, which enhances H3K27 trimethylation, and...

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Detalles Bibliográficos
Autores principales:	Li, X, Wu, Z, Mei, Q, Guo, M, Fu, X, Han, W
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Genetics and Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798955/ https://www.ncbi.nlm.nih.gov/pubmed/24022190 http://dx.doi.org/10.1038/bjc.2013.548

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