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The in situ local immune response, tumour senescence and proliferation in colorectal cancer
BACKGROUND: Immune cell infiltrates are important determinants of colorectal cancer (CRC) outcome. Their presence may be driven by tumour or host-specific factors. From previous studies in mice, senescence, a state of cell cycle arrest, may moderate tumour progression through upregulation of antitum...
Autores principales: | Roxburgh, C S, Richards, C H, MacDonald, A I, Powell, A G, McGlynn, L M, McMillan, D C, Horgan, P G, Edwards, J, Shiels, P G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798960/ https://www.ncbi.nlm.nih.gov/pubmed/24022192 http://dx.doi.org/10.1038/bjc.2013.556 |
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