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Surface proteomic analysis of osteosarcoma identifies EPHA2 as receptor for targeted drug delivery

BACKGROUND: Osteosarcoma (OS) is the most common bone tumour in children and adolescents. Despite aggressive therapy regimens, treatment outcomes are unsatisfactory. Targeted delivery of drugs can provide higher effective doses at the site of the tumour, ultimately improving the efficacy of existing...

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Detalles Bibliográficos
Autores principales:	PosthumaDeBoer, J, Piersma, S R, Pham, T V, van Egmond, P W, Knol, J C, Cleton-Jansen, A M, van Geer, M A, van Beusechem, V W, Kaspers, G J L, van Royen, B J, Jiménez, C R, Helder, M N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798973/ https://www.ncbi.nlm.nih.gov/pubmed/24064975 http://dx.doi.org/10.1038/bjc.2013.578

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