Contribution of BubR1 to oxidative stress-induced aneuploidy in p53-deficient cells

DNA aneuploidy is observed in various human tumors and is associated with the abnormal expression of spindle assembly checkpoint (SAC) proteins. Oxidative stress (OS) causes DNA damage and chromosome instability that may lead to carcinogenesis. OS is also suggested to contribute to an increase in an...

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Detalles Bibliográficos
Autores principales: Ikawa-Yoshida, Ayae, Ando, Koji, Oki, Eiji, Saeki, Hiroshi, Kumashiro, Ryuichi, Taketani, Kenji, Ida, Satoshi, Tokunaga, Eriko, Kitao, Hiroyuki, Morita, Masaru, Maehara, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Science Inc 2013
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799279/
https://www.ncbi.nlm.nih.gov/pubmed/24156017
http://dx.doi.org/10.1002/cam4.101

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