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RNA-dependent association with myosin IIA promotes F-actin-guided trafficking of the ELAV-like protein HuR to polysomes
The role of the mRNA-binding protein human antigen R (HuR) in stabilization and translation of AU-rich elements (ARE) containing mRNAs is well established. However, the trafficking of HuR and bound mRNA cargo, which comprises a fundamental requirement for the aforementioned HuR functions is only poo...
Autores principales: | Doller, Anke, Schulz, Sebastian, Pfeilschifter, Josef, Eberhardt, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799433/ https://www.ncbi.nlm.nih.gov/pubmed/23921630 http://dx.doi.org/10.1093/nar/gkt663 |
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