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Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively

Yeast 25S rRNA was reported to contain a single cytosine methylation (m(5)C). In the present study using a combination of RP-HPLC, mung bean nuclease assay and rRNA mutagenesis, we discovered that instead of one, yeast contains two m(5)C residues at position 2278 and 2870. Furthermore, we identified...

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Detalles Bibliográficos
Autores principales: Sharma, Sunny, Yang, Jun, Watzinger, Peter, Kötter, Peter, Entian, Karl-Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799443/
https://www.ncbi.nlm.nih.gov/pubmed/23913415
http://dx.doi.org/10.1093/nar/gkt679