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Yeast Nop2 and Rcm1 methylate C2870 and C2278 of the 25S rRNA, respectively
Yeast 25S rRNA was reported to contain a single cytosine methylation (m(5)C). In the present study using a combination of RP-HPLC, mung bean nuclease assay and rRNA mutagenesis, we discovered that instead of one, yeast contains two m(5)C residues at position 2278 and 2870. Furthermore, we identified...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799443/ https://www.ncbi.nlm.nih.gov/pubmed/23913415 http://dx.doi.org/10.1093/nar/gkt679 |