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Upstream mononucleotide A-repeats play a cis-regulatory role in mammals through the DICER1 and Ago proteins
A-repeats are the simplest form of tandem repeats and are found ubiquitously throughout genomes. These mononucleotide repeats have been widely believed to be non-functional ‘junk’ DNA. However, studies in yeasts suggest that A-repeats play crucial biological functions, and their role in humans remai...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799445/ https://www.ncbi.nlm.nih.gov/pubmed/23935075 http://dx.doi.org/10.1093/nar/gkt685 |