Cargando…

Direct assessment of transcription fidelity by high-resolution RNA sequencing

Cancerous and aging cells have long been thought to be impacted by transcription errors that cause genetic and epigenetic changes. Until now, a lack of methodology for directly assessing such errors hindered evaluation of their impact to the cells. We report a high-resolution Illumina RNA-seq method...

Descripción completa

Detalles Bibliográficos
Autores principales: Imashimizu, Masahiko, Oshima, Taku, Lubkowska, Lucyna, Kashlev, Mikhail
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799451/
https://www.ncbi.nlm.nih.gov/pubmed/23925128
http://dx.doi.org/10.1093/nar/gkt698