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Preventive and Therapeutic Efficacy of Finasteride and Dutasteride in TRAMP Mice

BACKGROUND: The prostate cancer prevention trial (PCPT) and Reduction by dutasteride of Prostate Cancer Events (REDUCE) trial found that 5α-reductase (5αR) inhibitors finasteride and dutasteride respectively, decreased prostate cancer prevalence but also increased the incidence of high-grade tumors....

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Detalles Bibliográficos
Autores principales:	Opoku-Acheampong, Alexander B., Unis, Dave, Henningson, Jamie N., Beck, Amanda P., Lindshield, Brian L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799703/ https://www.ncbi.nlm.nih.gov/pubmed/24204943 http://dx.doi.org/10.1371/journal.pone.0077738

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