Cargando…
Recovery from Slow Inactivation in K(+) Channels is Controlled by Water Molecules
The bacterial K(+) channel KcsA can be used to help elucidate questions about channel inactivation and recovery at the atomic level. Although KcsA contains only a pore domain, without voltage-sensing machinery, it has the structural elements necessary for ion conduction, activation and inactivation(...
Autores principales: | Ostmeyer, Jared, Chakrapani, Sudha, Pan, Albert C., Perozo, Eduardo, Roux, Benoît |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799803/ https://www.ncbi.nlm.nih.gov/pubmed/23892782 http://dx.doi.org/10.1038/nature12395 |
Ejemplares similares
-
Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel
por: Li, Jing, et al.
Publicado: (2018) -
On The Structural Basis of Modal Gating Behavior in K(+)
Channels
por: Chakrapani, Sudha, et al.
Publicado: (2010) -
Thermodynamic coupling between activation and inactivation gating in potassium channels revealed by free energy molecular dynamics simulations
por: Pan, Albert C., et al.
Publicado: (2011) -
Mechanism of C-type inactivation in the hERG potassium channel
por: Li, Jing, et al.
Publicado: (2021) -
A Quantitative Description of KcsA Gating II: Single-Channel Currents
por: Chakrapani, Sudha, et al.
Publicado: (2007)