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The Antifungal Eugenol Perturbs Dual Aromatic and Branched-Chain Amino Acid Permeases in the Cytoplasmic Membrane of Yeast

Eugenol is an aromatic component of clove oil that has therapeutic potential as an antifungal drug, although its mode of action and precise cellular target(s) remain ambiguous. To address this knowledge gap, a chemical-genetic profile analysis of eugenol was done using ∼4700 haploid Saccharomyces ce...

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Detalles Bibliográficos
Autores principales: Darvishi, Emad, Omidi, Mansoor, Bushehri, Ali Akbar Shahnejat, Golshani, Ashkan, Smith, Myron L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799837/
https://www.ncbi.nlm.nih.gov/pubmed/24204588
http://dx.doi.org/10.1371/journal.pone.0076028