Sigma-1 Receptor Chaperone at the ER-Mitochondrion Interface Mediates the Mitochondrion-ER-Nucleus Signaling for Cellular Survival

The membrane of the endoplasmic reticulum (ER) of a cell forms contacts directly with mitochondria whereby the contact is referred to as the mitochondrion-associated ER membrane or the MAM. Here we found that the MAM regulates cellular survival via an MAM-residing ER chaperone the sigma-1 receptor (...

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Detalles Bibliográficos
Autores principales: Mori, Tomohisa, Hayashi, Teruo, Hayashi, Eri, Su, Tsung-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799859/
https://www.ncbi.nlm.nih.gov/pubmed/24204710
http://dx.doi.org/10.1371/journal.pone.0076941

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