The integrated landscape of driver genomic alterations in glioblastoma

Glioblastoma remains one of the most challenging forms of cancer to treat. Here, we develop a computational platform that integrates the analysis of copy number variations and somatic mutations and unravels the landscape of in-frame gene fusions in glioblastoma. We find mutations with loss of hetero...

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Detalles Bibliográficos
Autores principales: Frattini, Veronique, Trifonov, Vladimir, Chan, Joseph Minhow, Castano, Angelica, Lia, Marie, Abate, Francesco, Keir, Stephen T., Ji, Alan X., Zoppoli, Pietro, Niola, Francesco, Danussi, Carla, Dolgalev, Igor, Porrati, Paola, Pellegatta, Serena, Heguy, Adriana, Gupta, Gaurav, Pisapia, David J., Canoll, Peter, Bruce, Jeffrey N., McLendon, Roger E., Yan, Hai, Aldape, Ken, Finocchiaro, Gaetano, Mikkelsen, Tom, Privé, Gilbert G., Bigner, Darell D., Lasorella, Anna, Rabadan, Raul, Iavarone, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799953/
https://www.ncbi.nlm.nih.gov/pubmed/23917401
http://dx.doi.org/10.1038/ng.2734

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