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Heterotrimeric G-Protein, G(α16), Is a Critical Downstream Effector of Non-Canonical Wnt Signaling and a Potent Inhibitor of Transformed Cell Growth in Non Small Cell Lung Cancer
G-protein-coupled receptors (GPCR) are the largest family of cell surface molecules that play important role/s in a number of biological and pathological processes including cancers. Earlier studies have highlighted the importance of Wnt7a signaling via its cognate receptor Frizzled9, a GPCR, in inh...
Autores principales: | Avasarala, Sreedevi, Bikkavilli, Rama Kamesh, Van Scoyk, Michelle, Zhang, Wei, Lapite, Ajibike, Hostetter, Logan, Byers, Joshua T., Heasley, Lynn E., Sohn, Jang Won, Winn, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800035/ https://www.ncbi.nlm.nih.gov/pubmed/24204697 http://dx.doi.org/10.1371/journal.pone.0076895 |
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