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Hidden specificity in an apparently non-specific RNA-binding protein

Nucleic acid binding proteins are generally viewed as either specific or non-specific, depending on characteristics of their binding sites in DNA or RNA (1,2). Most studies have focused on specific proteins, which identify cognate sites by binding with highest affinities to regions with defined sign...

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Detalles Bibliográficos
Autores principales: Guenther, Ulf-Peter, Yandek, Lindsay E., Niland, Courtney N., Campbell, Frank E., Anderson, David, Anderson, Vernon E., Harris, Michael E., Jankowsky, Eckhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800043/
https://www.ncbi.nlm.nih.gov/pubmed/24056935
http://dx.doi.org/10.1038/nature12543