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Verrucous Papillary Lesions: Dilemmas in Diagnosis and Terminology

Verrucous papillary lesions (VPLs) of oral cavity are diagnostically challenging as they include a spectrum of benign, potentially malignant, and frankly malignant lesions. A majority of the benign VPLs have viral aetiology and include commonly occurring squamous papilloma along with verruca vulgari...

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Autores principales: Kallarakkal, Thomas George, Ramanathan, Anand, Zain, Rosnah Binti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800582/
https://www.ncbi.nlm.nih.gov/pubmed/24223590
http://dx.doi.org/10.1155/2013/298249
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author Kallarakkal, Thomas George
Ramanathan, Anand
Zain, Rosnah Binti
author_facet Kallarakkal, Thomas George
Ramanathan, Anand
Zain, Rosnah Binti
author_sort Kallarakkal, Thomas George
collection PubMed
description Verrucous papillary lesions (VPLs) of oral cavity are diagnostically challenging as they include a spectrum of benign, potentially malignant, and frankly malignant lesions. A majority of the benign VPLs have viral aetiology and include commonly occurring squamous papilloma along with verruca vulgaris, focal epithelial hyperplasia, and condyloma. Current understanding of potentially malignant VPLs is perplexing and is primarily attributed to the use of confusing and unsatisfactory terminology. Clinically and histologically oral verrucous hyperplasia, a potentially malignant disorder, resembles oral verrucous carcinoma and may be indistinguishable from one another. The most reliable way to separate these entities on routine haematoxylin-eosin stained tissue sections is to recognize the exophytic growth patterns of oral verrucous hyperplasia from the combined exophytic and endophytic growth patterns associated with verrucous carcinoma. A review of the literature showed that there is a lot of confusion regarding the current clinical and histopathological guidelines to diagnose this potentially malignant entity. The criteria elaborated by different authors in establishing the diagnosis of oral verrucous hyperplasia are discussed in detail. A brief overview of the treatment modalities adopted is also discussed. The need for establishing a clear understanding of this potentially malignant entity is stressed as it may have far reaching implications on its management.
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spelling pubmed-38005822013-11-10 Verrucous Papillary Lesions: Dilemmas in Diagnosis and Terminology Kallarakkal, Thomas George Ramanathan, Anand Zain, Rosnah Binti Int J Dent Review Article Verrucous papillary lesions (VPLs) of oral cavity are diagnostically challenging as they include a spectrum of benign, potentially malignant, and frankly malignant lesions. A majority of the benign VPLs have viral aetiology and include commonly occurring squamous papilloma along with verruca vulgaris, focal epithelial hyperplasia, and condyloma. Current understanding of potentially malignant VPLs is perplexing and is primarily attributed to the use of confusing and unsatisfactory terminology. Clinically and histologically oral verrucous hyperplasia, a potentially malignant disorder, resembles oral verrucous carcinoma and may be indistinguishable from one another. The most reliable way to separate these entities on routine haematoxylin-eosin stained tissue sections is to recognize the exophytic growth patterns of oral verrucous hyperplasia from the combined exophytic and endophytic growth patterns associated with verrucous carcinoma. A review of the literature showed that there is a lot of confusion regarding the current clinical and histopathological guidelines to diagnose this potentially malignant entity. The criteria elaborated by different authors in establishing the diagnosis of oral verrucous hyperplasia are discussed in detail. A brief overview of the treatment modalities adopted is also discussed. The need for establishing a clear understanding of this potentially malignant entity is stressed as it may have far reaching implications on its management. Hindawi Publishing Corporation 2013 2013-09-24 /pmc/articles/PMC3800582/ /pubmed/24223590 http://dx.doi.org/10.1155/2013/298249 Text en Copyright © 2013 Thomas George Kallarakkal et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Kallarakkal, Thomas George
Ramanathan, Anand
Zain, Rosnah Binti
Verrucous Papillary Lesions: Dilemmas in Diagnosis and Terminology
title Verrucous Papillary Lesions: Dilemmas in Diagnosis and Terminology
title_full Verrucous Papillary Lesions: Dilemmas in Diagnosis and Terminology
title_fullStr Verrucous Papillary Lesions: Dilemmas in Diagnosis and Terminology
title_full_unstemmed Verrucous Papillary Lesions: Dilemmas in Diagnosis and Terminology
title_short Verrucous Papillary Lesions: Dilemmas in Diagnosis and Terminology
title_sort verrucous papillary lesions: dilemmas in diagnosis and terminology
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800582/
https://www.ncbi.nlm.nih.gov/pubmed/24223590
http://dx.doi.org/10.1155/2013/298249
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