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Inflammation on the Cervical Papanicolaou Smear: Evidence for Infection in Asymptomatic Women?

Background. The significance of the possible presence of infection on the Pap smear of asymptomatic women based on cytological criteria is practically unknown. Materials and Methods. A total of 1117 asymptomatic nonpregnant women had Pap smear tests and vaginal as well as cervical cultures completed...

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Autores principales: Baka, Stavroula, Tsirmpa, Ioanna, Chasiakou, Anthia, Tsouma, Iliana, Politi, Ekaterina, Gennimata, Vassiliki, Kouskouni, Evangelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800589/
https://www.ncbi.nlm.nih.gov/pubmed/24204103
http://dx.doi.org/10.1155/2013/184302
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author Baka, Stavroula
Tsirmpa, Ioanna
Chasiakou, Anthia
Tsouma, Iliana
Politi, Ekaterina
Gennimata, Vassiliki
Kouskouni, Evangelia
author_facet Baka, Stavroula
Tsirmpa, Ioanna
Chasiakou, Anthia
Tsouma, Iliana
Politi, Ekaterina
Gennimata, Vassiliki
Kouskouni, Evangelia
author_sort Baka, Stavroula
collection PubMed
description Background. The significance of the possible presence of infection on the Pap smear of asymptomatic women based on cytological criteria is practically unknown. Materials and Methods. A total of 1117 asymptomatic nonpregnant women had Pap smear tests and vaginal as well as cervical cultures completed (622 with and 495 without inflammation on the Pap smear). Results. Out of the 622 women with inflammation on Pap test, 251 (40.4%) had negative cultures (normal flora present), while 371 (59.6%) women had positive cultures with different pathogens. In contrast, the group of women without inflammation on Pap test displayed significantly increased percentage of negative cultures (67.1%, P < 0.001) and decreased percentage of positive cultures (32.9%, P < 0.001). Bacterial vaginosis was diagnosed more frequently in both groups and significantly more in the group with inflammation on Pap smear compared to the group without inflammation (P < 0.02). Conclusions. A report of inflammatory changes on the cervical Pap smear cannot be used to reliably predict the presence of a genital tract infection, especially in asymptomatic women. Nevertheless, the isolation of different pathogens in about 60% of the women with inflammation on the Pap smear cannot be overlooked and must be regarded with concern.
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spelling pubmed-38005892013-11-07 Inflammation on the Cervical Papanicolaou Smear: Evidence for Infection in Asymptomatic Women? Baka, Stavroula Tsirmpa, Ioanna Chasiakou, Anthia Tsouma, Iliana Politi, Ekaterina Gennimata, Vassiliki Kouskouni, Evangelia Infect Dis Obstet Gynecol Research Article Background. The significance of the possible presence of infection on the Pap smear of asymptomatic women based on cytological criteria is practically unknown. Materials and Methods. A total of 1117 asymptomatic nonpregnant women had Pap smear tests and vaginal as well as cervical cultures completed (622 with and 495 without inflammation on the Pap smear). Results. Out of the 622 women with inflammation on Pap test, 251 (40.4%) had negative cultures (normal flora present), while 371 (59.6%) women had positive cultures with different pathogens. In contrast, the group of women without inflammation on Pap test displayed significantly increased percentage of negative cultures (67.1%, P < 0.001) and decreased percentage of positive cultures (32.9%, P < 0.001). Bacterial vaginosis was diagnosed more frequently in both groups and significantly more in the group with inflammation on Pap smear compared to the group without inflammation (P < 0.02). Conclusions. A report of inflammatory changes on the cervical Pap smear cannot be used to reliably predict the presence of a genital tract infection, especially in asymptomatic women. Nevertheless, the isolation of different pathogens in about 60% of the women with inflammation on the Pap smear cannot be overlooked and must be regarded with concern. Hindawi Publishing Corporation 2013 2013-09-24 /pmc/articles/PMC3800589/ /pubmed/24204103 http://dx.doi.org/10.1155/2013/184302 Text en Copyright © 2013 Stavroula Baka et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Baka, Stavroula
Tsirmpa, Ioanna
Chasiakou, Anthia
Tsouma, Iliana
Politi, Ekaterina
Gennimata, Vassiliki
Kouskouni, Evangelia
Inflammation on the Cervical Papanicolaou Smear: Evidence for Infection in Asymptomatic Women?
title Inflammation on the Cervical Papanicolaou Smear: Evidence for Infection in Asymptomatic Women?
title_full Inflammation on the Cervical Papanicolaou Smear: Evidence for Infection in Asymptomatic Women?
title_fullStr Inflammation on the Cervical Papanicolaou Smear: Evidence for Infection in Asymptomatic Women?
title_full_unstemmed Inflammation on the Cervical Papanicolaou Smear: Evidence for Infection in Asymptomatic Women?
title_short Inflammation on the Cervical Papanicolaou Smear: Evidence for Infection in Asymptomatic Women?
title_sort inflammation on the cervical papanicolaou smear: evidence for infection in asymptomatic women?
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800589/
https://www.ncbi.nlm.nih.gov/pubmed/24204103
http://dx.doi.org/10.1155/2013/184302
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