Destruxin B Isolated from Entomopathogenic Fungus Metarhizium anisopliae Induces Apoptosis via a Bcl-2 Family-Dependent Mitochondrial Pathway in Human Nonsmall Cell Lung Cancer Cells

Destruxin B, isolated from entomopathogenic fungus Metarhizium anisopliae, is one of the cyclodepsipeptides with insecticidal and anticancer activities. In this study, destruxin B was extracted and purified by ion-exchange chromatography, silica gel chromatography, and semipreparative high-performan...

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Detalles Bibliográficos
Autores principales: Wu, Chun-Chi, Chen, Tzu-Hsiu, Liu, Bing-Lan, Wu, Li-Chen, Chen, Yung-Ching, Tzeng, Yew-Min, Hsu, Shih-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800607/
https://www.ncbi.nlm.nih.gov/pubmed/24204395
http://dx.doi.org/10.1155/2013/548929

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