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Is Surgery in the Elderly for Oesophageal Cancer Justifiable? Results from a Single Centre

Aims. Advanced age is an identified risk factor for patients undergoing oncological surgical resection. The surgery for oesophageal cancer is associated with significant morbidity and mortality. Our aim was to study the operative management of elderly patients (≥70 years) at a single institute. Meth...

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Autores principales: Mirza, A., Pritchard, S., Welch, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800610/
https://www.ncbi.nlm.nih.gov/pubmed/24205444
http://dx.doi.org/10.1155/2013/609252
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author Mirza, A.
Pritchard, S.
Welch, I.
author_facet Mirza, A.
Pritchard, S.
Welch, I.
author_sort Mirza, A.
collection PubMed
description Aims. Advanced age is an identified risk factor for patients undergoing oncological surgical resection. The surgery for oesophageal cancer is associated with significant morbidity and mortality. Our aim was to study the operative management of elderly patients (≥70 years) at a single institute. Methods. The data was collected from 206 patients who have undergone operative resection of oesophageal cancer. The demographic, operative, histological, and postoperative follow-up of all patients were analysed. Results. A total of 46 patients of ≥70 years who had surgical resection for oesophageal cancer were identified. Patients ≥70 years had poor overall survival (P = 0.00). Also elderly patients with nodal involvement had poor survival (P = 0.04). Age at the time of surgery had no impact on the incidence of postoperative complication and inpatient mortality. Both the univariate and multivariate analyses showed age, nodal stage, and positive resection margins as independent prognostic factors for patients undergoing surgery for oesophageal cancer. Conclusions. Advanced age is associated with poor outcome following oesophageal resection. However, the optimisation of both preoperative and postoperative care can significantly improve outcomes. The decision of operative management should be individualised. Age should be considered as one of the factors in surgical resection of oesophageal cancer in the elderly patients.
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spelling pubmed-38006102013-11-07 Is Surgery in the Elderly for Oesophageal Cancer Justifiable? Results from a Single Centre Mirza, A. Pritchard, S. Welch, I. ISRN Surg Research Article Aims. Advanced age is an identified risk factor for patients undergoing oncological surgical resection. The surgery for oesophageal cancer is associated with significant morbidity and mortality. Our aim was to study the operative management of elderly patients (≥70 years) at a single institute. Methods. The data was collected from 206 patients who have undergone operative resection of oesophageal cancer. The demographic, operative, histological, and postoperative follow-up of all patients were analysed. Results. A total of 46 patients of ≥70 years who had surgical resection for oesophageal cancer were identified. Patients ≥70 years had poor overall survival (P = 0.00). Also elderly patients with nodal involvement had poor survival (P = 0.04). Age at the time of surgery had no impact on the incidence of postoperative complication and inpatient mortality. Both the univariate and multivariate analyses showed age, nodal stage, and positive resection margins as independent prognostic factors for patients undergoing surgery for oesophageal cancer. Conclusions. Advanced age is associated with poor outcome following oesophageal resection. However, the optimisation of both preoperative and postoperative care can significantly improve outcomes. The decision of operative management should be individualised. Age should be considered as one of the factors in surgical resection of oesophageal cancer in the elderly patients. Hindawi Publishing Corporation 2013-09-24 /pmc/articles/PMC3800610/ /pubmed/24205444 http://dx.doi.org/10.1155/2013/609252 Text en Copyright © 2013 A. Mirza et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Mirza, A.
Pritchard, S.
Welch, I.
Is Surgery in the Elderly for Oesophageal Cancer Justifiable? Results from a Single Centre
title Is Surgery in the Elderly for Oesophageal Cancer Justifiable? Results from a Single Centre
title_full Is Surgery in the Elderly for Oesophageal Cancer Justifiable? Results from a Single Centre
title_fullStr Is Surgery in the Elderly for Oesophageal Cancer Justifiable? Results from a Single Centre
title_full_unstemmed Is Surgery in the Elderly for Oesophageal Cancer Justifiable? Results from a Single Centre
title_short Is Surgery in the Elderly for Oesophageal Cancer Justifiable? Results from a Single Centre
title_sort is surgery in the elderly for oesophageal cancer justifiable? results from a single centre
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800610/
https://www.ncbi.nlm.nih.gov/pubmed/24205444
http://dx.doi.org/10.1155/2013/609252
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