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Influenza Virus Specific CD8(+) T Cells Exacerbate Infection Following High Dose Influenza Challenge of Aged Mice
Influenza viruses cause severe illnesses and death, mainly in the aged population. Protection afforded by licensed vaccines through subtype-specific neutralizing antibodies is incomplete, especially when the vaccine antigens fail to closely match those of the circulating viral strains. Efforts are u...
Autores principales: | Parzych, E. M., DiMenna, L. J., Latimer, B. P., Small, J. C., Kannan, S., Manson, B., Lasaro, M. O., Wherry, E. J., Ertl, H. C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800650/ https://www.ncbi.nlm.nih.gov/pubmed/24187666 http://dx.doi.org/10.1155/2013/876314 |
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