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In Vitro Activation and Inhibition of Recombinant EGFR Tyrosine Kinase Expressed in Escherichia coli

The present work concerns the heterologous expression of the intracellular domain harbouring the tyrosine kinase activity of the epidermal growth factor receptor (EGFR). Protein expression was improved thanks to the deletion of a 13-amino acid peptide of the juxtamembrane region (JM). The recombinan...

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Detalles Bibliográficos
Autores principales:	Elloumi-Mseddi, Jihene, Jellali, Karim, Aifa, Sami
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800664/ https://www.ncbi.nlm.nih.gov/pubmed/24187524 http://dx.doi.org/10.1155/2013/807284

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