PA01.59. Evaluation of rasayana effect of vayasthapana drugs

PURPOSE: The present study is designed on the hypothesis that stress, life style and dietary habits may have an impact on ageing. It aims to explain how the Vayasthapana drugs affect premature ageing by promoting mental and physical health, longevity and also by improving immunity. The study is intended to focus on how the Vayasthapana drugs clinically help in achieving a sense of general well being. METHOD: The clinical study was carried out on 50 male volunteers in the age group of 45 55yrs. Vayasthapana (Amrutha, Ahbaya, Dhatri, Mukta, Jivanti, Atirasa, Mandukaparni and Punarnava) compound consisting of 8 out of 10 herbs suggested by Acharya Charaka, in the form of aqueous extract put into capsule form each of 500 mg and administered with a dosage of 2 caps thrice in a day for a period of 90 days. The bio chemical investigations, Hamilton Anxiety Rating Scale and other physical and mental health parameters were assessed before the commencement of the trial as well as at the end of 90 days. Invitro studies have been carried out to assess the antioxidant property of vayasthapana compound. RESULT: Invitro studies carried out have shown significant anti oxidant activity. Amongst the biological factors, an improvement in the lusture of the body, moderate relief from joint pains, muscular cramps, loss of appetite and constipation are observed. Mild relief has been observed in anxiety, stress and loss of concentration. It is observed that there is a significant increase in Hb%, RBC and Total proteins. CONCLUSION: Undoubtedly Rasayana chikitsa is the strength of Ayurveda to meet the upcoming challenges of age related degenerative problems. The present study has also confirmed it and the volunteers who have participated in the study have reported the feeling of well being with the improvement of bio chemical indices.