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PA01.62. Mukta-sukti bhasma; nectar for acid peptic disorders, w.s.r to its anti-ulcer activity - an experimental study
PURPOSE: Mukta Shukti (Pearl oyster shell); a sudha varga dravya, attains better therapeutic properties with proper sodhana and marana processes. It is indicated in Amlapitta, Parinamashoola and Annadravashoola. Acharya Susruta mentioned; Amla is the property of Vidagdha Pitta. The term Amlapitta ma...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800866/ |
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author | Sreejith, R |
author_facet | Sreejith, R |
author_sort | Sreejith, R |
collection | PubMed |
description | PURPOSE: Mukta Shukti (Pearl oyster shell); a sudha varga dravya, attains better therapeutic properties with proper sodhana and marana processes. It is indicated in Amlapitta, Parinamashoola and Annadravashoola. Acharya Susruta mentioned; Amla is the property of Vidagdha Pitta. The term Amlapitta may be correlated with Acid reflux syndrome which comprises of various types of Gastro esophageal reflux diseases like Gastritis, Peptic ulcer etc. A peptic ulcer is a sore on the lining of the stomach or duodenum, the beginning of the small intestine. A bacterium called Helicobacter pylori is a major cause of peptic ulcers. An attempt was made in this regard to establish standards to assure quality and to assess antiulcer activity of Mukta Sukti Bhasma. METHOD: Mukta sukti Bhasma prepared as per Rasatarangini and subjected to Atomic absorption spectroscopy (AAS) and X ray diffraction (XRD). Anti ulcer activity of Mukta sukti Bhasma in Albino rats by Aspirin induced gastric ulcer. Sucralfate as standard group and normal food water as control group used for the comparison. RESULT: Mukta sukti Bhasma showed highly significant Anti ulcer activity than control group. The alkaline pH and chemical components might have contributed by inhibiting secretions, neutralizing the acidity and reducing size of the ulcerative lesions. Presence of Calcium (Ca), Magnesium (Mg), Manganese (Mn), Iron (Fe), Potassium (K), Aluminum (Al), Copper (Cu), Sodium (Na) and Zinc (Zn) were detected in raw Mukta sukti and Mukta sukti Bhasma. X ray diffraction shown face centered Cubic, hexagonal, tetragonal and monoclinic crystal structures. CONCLUSION: In aspirin induced model, the Mukta sukti Bhasma and standard group (Sucralfate) showed highly significant Anti ulcer activity than control group (food water). The Mukta sukti Bhasma showed highly significant Anti ulcer activity than standard group (Sucralfate) when compared. This experimental study has given scientific evidence for the claim in the ancient text regarding the Anti ulcer property of Mukta sukti Bhasma which gives scope for conducting clinical study. |
format | Online Article Text |
id | pubmed-3800866 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-38008662013-10-25 PA01.62. Mukta-sukti bhasma; nectar for acid peptic disorders, w.s.r to its anti-ulcer activity - an experimental study Sreejith, R Anc Sci Life Poster Presentation PURPOSE: Mukta Shukti (Pearl oyster shell); a sudha varga dravya, attains better therapeutic properties with proper sodhana and marana processes. It is indicated in Amlapitta, Parinamashoola and Annadravashoola. Acharya Susruta mentioned; Amla is the property of Vidagdha Pitta. The term Amlapitta may be correlated with Acid reflux syndrome which comprises of various types of Gastro esophageal reflux diseases like Gastritis, Peptic ulcer etc. A peptic ulcer is a sore on the lining of the stomach or duodenum, the beginning of the small intestine. A bacterium called Helicobacter pylori is a major cause of peptic ulcers. An attempt was made in this regard to establish standards to assure quality and to assess antiulcer activity of Mukta Sukti Bhasma. METHOD: Mukta sukti Bhasma prepared as per Rasatarangini and subjected to Atomic absorption spectroscopy (AAS) and X ray diffraction (XRD). Anti ulcer activity of Mukta sukti Bhasma in Albino rats by Aspirin induced gastric ulcer. Sucralfate as standard group and normal food water as control group used for the comparison. RESULT: Mukta sukti Bhasma showed highly significant Anti ulcer activity than control group. The alkaline pH and chemical components might have contributed by inhibiting secretions, neutralizing the acidity and reducing size of the ulcerative lesions. Presence of Calcium (Ca), Magnesium (Mg), Manganese (Mn), Iron (Fe), Potassium (K), Aluminum (Al), Copper (Cu), Sodium (Na) and Zinc (Zn) were detected in raw Mukta sukti and Mukta sukti Bhasma. X ray diffraction shown face centered Cubic, hexagonal, tetragonal and monoclinic crystal structures. CONCLUSION: In aspirin induced model, the Mukta sukti Bhasma and standard group (Sucralfate) showed highly significant Anti ulcer activity than control group (food water). The Mukta sukti Bhasma showed highly significant Anti ulcer activity than standard group (Sucralfate) when compared. This experimental study has given scientific evidence for the claim in the ancient text regarding the Anti ulcer property of Mukta sukti Bhasma which gives scope for conducting clinical study. Medknow Publications & Media Pvt Ltd 2012-12 /pmc/articles/PMC3800866/ Text en Copyright: © 2012 Sreejith; licensee Ancient Science of Life. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Poster Presentation Sreejith, R PA01.62. Mukta-sukti bhasma; nectar for acid peptic disorders, w.s.r to its anti-ulcer activity - an experimental study |
title | PA01.62. Mukta-sukti bhasma; nectar for acid peptic disorders, w.s.r to its anti-ulcer activity - an experimental study |
title_full | PA01.62. Mukta-sukti bhasma; nectar for acid peptic disorders, w.s.r to its anti-ulcer activity - an experimental study |
title_fullStr | PA01.62. Mukta-sukti bhasma; nectar for acid peptic disorders, w.s.r to its anti-ulcer activity - an experimental study |
title_full_unstemmed | PA01.62. Mukta-sukti bhasma; nectar for acid peptic disorders, w.s.r to its anti-ulcer activity - an experimental study |
title_short | PA01.62. Mukta-sukti bhasma; nectar for acid peptic disorders, w.s.r to its anti-ulcer activity - an experimental study |
title_sort | pa01.62. mukta-sukti bhasma; nectar for acid peptic disorders, w.s.r to its anti-ulcer activity - an experimental study |
topic | Poster Presentation |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3800866/ |
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