PA01.09. Efficacy of ayurvedic formulations in allergic asthma patients with special reference to elevation of TIgE

PURPOSE: Allergic Asthma Tamaka swasa is one of the most distressing common diseases that affect a sizable number of world populations. Internal and external allergens such as environmental change, pollutants and unsuitable foods are believed to be the predisposing factors which sensitize the immune system of the body and trigger production of the antibody Immunoglobulin E. These result in sneezing, running nose, irritation of eyes, inflammation of bronchial mucosa and wheezing. Ayurvedic formulations such as Dasamoolakatuthrayam kwatha, Vyoshadi vatakam, Swasanandam gutika and Swasa kalpa are widely used by Ayurvedic physicians and clinically proven to have anti allergic effect. They relieve bronco spasm, airway block, sneezing and running nose. Current study was aimed at proving the efficacy of these formulations in Allergic Asthma. METHOD: Patients diagnosed with Allergic Asthma were chosen for clinical study. A total of 38 patients of either sex ranging from the age of 4 to 48 were selected for the study. All the patients were tested for their blood level TIgE. Most of them were found to have elevated blood level TIgE. Every patient was given Dasamoolakatuthrayam kwatha, Vyoshadi vatakam, Swasanandam gutika and Swasa kalpa orally for 6 8 weeks and the progress was observed. The observations were recorded based on subjective and objective methods. RESULT: It was construed from the results that the trial medicines had significantanti allergic, expectorant, bronco dilatation and overall reduction in the symptoms of Allergic Asthma in the analyzed patients. By the end of 8 weeks 16 out of 38 patients had significant recovery from the symptoms, 18 had good control of the ailment while the rest 4 displayed poor progress. CONCLUSION: The study vividly fortified the therapeutic efficacy of the trial drugs in the management of Allergic Asthma. Besides relieving the symptoms, the drugs significantly reduced the elevated TIgE in the blood.