PA01.19. Clinical evaluation of pandughni vati & dhatri lauha vati on garbhini pandu (iron deficiency anaemia in pregnancy

PURPOSE: The desire to have a healthy progeny is innate & very intense in every living being. The hectic life and tremendous stress in today's world has made the conception & continuation of pregnancy to term very difficult. Anaemia is one of the common disease conditions which affect a pregnant woman. In Ayurvedic classics anaemia in pregnancy is taken under the Rasa Pradoshaja Vikara. It is also a Santharpanotha Vikara. METHOD: Total 26 patients were registered from O.P.D. And I.P.D. of the department of Streeroga & Prasootitantra, out of them 4 patients were discontinued. They were randomly divided in to two groups; Group A (n 12) Pandughni Vati 2 tablets of 250mg tds and Group B (n 10) Dhatri Lauha Vati 1 tablet of 250mg tds. Dhatri Lauha Vati was selected for the present study due to its Pandughna, Prinana, Raktaprasadana properties. AYUSH department has developed a compound formulation Pandughni Vati. As a part of its clinical trials the same drug was selected for present study. RESULT: Group A The result observed in Shwasa (dyspnoea) (60%) and Hridrava (palpitation) (53.33%) were highly significant statistically (<0.001). Daurbalya (33.33%), Shrama (fatigue) (40%), Aruchi (anorexia) (28.57%) and Pindikodvestana (55.55%) were decreased significant statistically (<0.05) whereas in Panduta (pallor) (24%) it was not significant. In Group B, results observed were highly significant statistically (<0.001) in Panduta (pallor) (50%) and Shwasa (dyspnoea) (56.25%). The results in Shrama (fatigue) (61.54%), Hridrava (palpitation) (55.55%), Aruchi (anorexia) (42.85%), Pindikodvestan, (49.49%) were significant CONCLUSION: On comparing the effect of therapy study was finding better percentage improvement in-group B consistently in most of subjective and objective parameters. So it can be said that Dhatri Lauha Vati has somewhatbetter results, proving it better to Pandughni Vati.