Sarcophyolides B–E, New Cembranoids from the Soft Coral Sarcophyton elegans

Four new cembrane-type diterpenoids, sarcophyolides B–E (1–4), along with 11 known analogues were isolated from the soft coral Sarcophyton elegans. The structures of new compounds 1–4 were established on the basis of spectroscopic analysis and chemical conversion. The new cembranoids sarcophyolides...

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Autores principales: Xi, Zhifang, Bie, Wei, Chen, Wei, Liu, Dong, van Ofwegen, Leen, Proksch, Peter, Lin, Wenhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801120/
https://www.ncbi.nlm.nih.gov/pubmed/24065160
http://dx.doi.org/10.3390/md11093186
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author Xi, Zhifang
Bie, Wei
Chen, Wei
Liu, Dong
van Ofwegen, Leen
Proksch, Peter
Lin, Wenhan
author_facet Xi, Zhifang
Bie, Wei
Chen, Wei
Liu, Dong
van Ofwegen, Leen
Proksch, Peter
Lin, Wenhan
author_sort Xi, Zhifang
collection PubMed
description Four new cembrane-type diterpenoids, sarcophyolides B–E (1–4), along with 11 known analogues were isolated from the soft coral Sarcophyton elegans. The structures of new compounds 1–4 were established on the basis of spectroscopic analysis and chemical conversion. The new cembranoids sarcophyolides B (1) and lobocrasol were found to exhibit potent inhibition against A2780 human ovarian tumor cells.
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spelling pubmed-38011202013-10-22 Sarcophyolides B–E, New Cembranoids from the Soft Coral Sarcophyton elegans Xi, Zhifang Bie, Wei Chen, Wei Liu, Dong van Ofwegen, Leen Proksch, Peter Lin, Wenhan Mar Drugs Article Four new cembrane-type diterpenoids, sarcophyolides B–E (1–4), along with 11 known analogues were isolated from the soft coral Sarcophyton elegans. The structures of new compounds 1–4 were established on the basis of spectroscopic analysis and chemical conversion. The new cembranoids sarcophyolides B (1) and lobocrasol were found to exhibit potent inhibition against A2780 human ovarian tumor cells. MDPI 2013-08-26 /pmc/articles/PMC3801120/ /pubmed/24065160 http://dx.doi.org/10.3390/md11093186 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Xi, Zhifang
Bie, Wei
Chen, Wei
Liu, Dong
van Ofwegen, Leen
Proksch, Peter
Lin, Wenhan
Sarcophyolides B–E, New Cembranoids from the Soft Coral Sarcophyton elegans
title Sarcophyolides B–E, New Cembranoids from the Soft Coral Sarcophyton elegans
title_full Sarcophyolides B–E, New Cembranoids from the Soft Coral Sarcophyton elegans
title_fullStr Sarcophyolides B–E, New Cembranoids from the Soft Coral Sarcophyton elegans
title_full_unstemmed Sarcophyolides B–E, New Cembranoids from the Soft Coral Sarcophyton elegans
title_short Sarcophyolides B–E, New Cembranoids from the Soft Coral Sarcophyton elegans
title_sort sarcophyolides b–e, new cembranoids from the soft coral sarcophyton elegans
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801120/
https://www.ncbi.nlm.nih.gov/pubmed/24065160
http://dx.doi.org/10.3390/md11093186
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