Secondary Metabolites from the Soft Coral Sinularia arborea

Two new 13-hydroxycembrane diterpenoids, arbolides A (1) and B (2), along with a known trihydroxysteroid, crassarosterol A (3), were isolated from the soft coral Sinularia arborea. The structures of new cembranes 1 and 2 were elucidated by spectroscopic methods. Steroid 3 was found to exhibit cytoto...

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Autores principales: Chen, Kuan-Hua, Dai, Chang-Feng, Lu, Mei-Chin, Li, Jan-Jung, Chen, Jih-Jung, Chang, Yu-Chia, Su, Yin-Di, Wang, Wei-Hsien, Sung, Ping-Jyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801123/
https://www.ncbi.nlm.nih.gov/pubmed/24005902
http://dx.doi.org/10.3390/md11093372
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author Chen, Kuan-Hua
Dai, Chang-Feng
Lu, Mei-Chin
Li, Jan-Jung
Chen, Jih-Jung
Chang, Yu-Chia
Su, Yin-Di
Wang, Wei-Hsien
Sung, Ping-Jyun
author_facet Chen, Kuan-Hua
Dai, Chang-Feng
Lu, Mei-Chin
Li, Jan-Jung
Chen, Jih-Jung
Chang, Yu-Chia
Su, Yin-Di
Wang, Wei-Hsien
Sung, Ping-Jyun
author_sort Chen, Kuan-Hua
collection PubMed
description Two new 13-hydroxycembrane diterpenoids, arbolides A (1) and B (2), along with a known trihydroxysteroid, crassarosterol A (3), were isolated from the soft coral Sinularia arborea. The structures of new cembranes 1 and 2 were elucidated by spectroscopic methods. Steroid 3 was found to exhibit cytotoxicity toward K562 and MOLT-4 leukemia.
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spelling pubmed-38011232013-10-22 Secondary Metabolites from the Soft Coral Sinularia arborea Chen, Kuan-Hua Dai, Chang-Feng Lu, Mei-Chin Li, Jan-Jung Chen, Jih-Jung Chang, Yu-Chia Su, Yin-Di Wang, Wei-Hsien Sung, Ping-Jyun Mar Drugs Communication Two new 13-hydroxycembrane diterpenoids, arbolides A (1) and B (2), along with a known trihydroxysteroid, crassarosterol A (3), were isolated from the soft coral Sinularia arborea. The structures of new cembranes 1 and 2 were elucidated by spectroscopic methods. Steroid 3 was found to exhibit cytotoxicity toward K562 and MOLT-4 leukemia. MDPI 2013-09-03 /pmc/articles/PMC3801123/ /pubmed/24005902 http://dx.doi.org/10.3390/md11093372 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Communication
Chen, Kuan-Hua
Dai, Chang-Feng
Lu, Mei-Chin
Li, Jan-Jung
Chen, Jih-Jung
Chang, Yu-Chia
Su, Yin-Di
Wang, Wei-Hsien
Sung, Ping-Jyun
Secondary Metabolites from the Soft Coral Sinularia arborea
title Secondary Metabolites from the Soft Coral Sinularia arborea
title_full Secondary Metabolites from the Soft Coral Sinularia arborea
title_fullStr Secondary Metabolites from the Soft Coral Sinularia arborea
title_full_unstemmed Secondary Metabolites from the Soft Coral Sinularia arborea
title_short Secondary Metabolites from the Soft Coral Sinularia arborea
title_sort secondary metabolites from the soft coral sinularia arborea
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801123/
https://www.ncbi.nlm.nih.gov/pubmed/24005902
http://dx.doi.org/10.3390/md11093372
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