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Co-Receptor CD8-Mediated Modulation of T-Cell Receptor Functional Sensitivity and Epitope Recognition Degeneracy

The interaction between T-cell receptors (TCRs) and peptide epitopes is highly degenerate: a TCR is capable of interacting productively with a wide range of different peptide ligands, involving not only cross-reactivity proper (similar epitopes elicit strong responses), but also polyspecificity (lig...

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Detalles Bibliográficos
Autores principales:	Szomolay, Barbara, Williams, Tamsin, Wooldridge, Linda, van den Berg, Hugo Antonius
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3801161/ https://www.ncbi.nlm.nih.gov/pubmed/24151493 http://dx.doi.org/10.3389/fimmu.2013.00329

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