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Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors

Lineage tracing approaches have provided new insights into the cellular mechanisms that support tissue homeostasis in mice. However, the relevance of these discoveries to human epithelial homeostasis and its alterations in disease is unknown. By developing a novel quantitative approach for the analy...

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Detalles Bibliográficos
Autores principales: Teixeira, Vitor H, Nadarajan, Parthiban, Graham, Trevor A, Pipinikas, Christodoulos P, Brown, James M, Falzon, Mary, Nye, Emma, Poulsom, Richard, Lawrence, David, Wright, Nicholas A, McDonald, Stuart, Giangreco, Adam, Simons, Benjamin D, Janes, Sam M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804062/
https://www.ncbi.nlm.nih.gov/pubmed/24151545
http://dx.doi.org/10.7554/eLife.00966