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Stochastic homeostasis in human airway epithelium is achieved by neutral competition of basal cell progenitors
Lineage tracing approaches have provided new insights into the cellular mechanisms that support tissue homeostasis in mice. However, the relevance of these discoveries to human epithelial homeostasis and its alterations in disease is unknown. By developing a novel quantitative approach for the analy...
Autores principales: | Teixeira, Vitor H, Nadarajan, Parthiban, Graham, Trevor A, Pipinikas, Christodoulos P, Brown, James M, Falzon, Mary, Nye, Emma, Poulsom, Richard, Lawrence, David, Wright, Nicholas A, McDonald, Stuart, Giangreco, Adam, Simons, Benjamin D, Janes, Sam M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804062/ https://www.ncbi.nlm.nih.gov/pubmed/24151545 http://dx.doi.org/10.7554/eLife.00966 |
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