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The Transcription Factor MAZR Preferentially Acts as a Transcriptional Repressor in Mast Cells and Plays a Minor Role in the Regulation of Effector Functions in Response to FcεRI Stimulation
Mast cells are key players in type I hypersensitivity reactions in humans and mice and their activity has to be tightly controlled. Previous studies implicated the transcription factor MAZR in the regulation of mast cell function. To study the role of MAZR in mast cells, we generated a conditional M...
Autores principales: | Abramova, Anastasia, Sakaguchi, Shinya, Schebesta, Alexandra, Hassan, Hammad, Boucheron, Nicole, Valent, Peter, Roers, Axel, Ellmeier, Wilfried |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804165/ https://www.ncbi.nlm.nih.gov/pubmed/24204913 http://dx.doi.org/10.1371/journal.pone.0077677 |
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