Comparison of resazurin microtiter assay performance and BACTEC MGIT 960 in the susceptibility testing of Brazilian clinical isolates of Mycobacterium tuberculosis to four first-line drugs

We assessed the performance of REMA in comparison with BACTEC MGIT 960 in the susceptibility testing of 80 Mycobacterium tuberculosis clinical isolates from Clemente Ferreira Institute against four drugs. REMA proved to be a rapid and accurate method, providing excellent correlation with BACTEC MGIT...

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Detalles Bibliográficos
Autores principales: Miyata, Marcelo, Pavan, Fernando Rogério, Sato, Daisy Nakamura, Marino, Leonardo Biancolino, Hirata, Mario Hiroyuki, Cardoso, Rosilene Fressati, de Melo, Fernando Augusto Fiúza, Leite, Clarice Queico Fujimura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Brazilian Society of Microbiology 2013
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3804211/
https://www.ncbi.nlm.nih.gov/pubmed/24159317
http://dx.doi.org/10.1590/S1517-83822013005000028
Descripción
Sumario:We assessed the performance of REMA in comparison with BACTEC MGIT 960 in the susceptibility testing of 80 Mycobacterium tuberculosis clinical isolates from Clemente Ferreira Institute against four drugs. REMA proved to be a rapid and accurate method, providing excellent correlation with BACTEC MGIT 960, with the exception of results for the ethambutol drug.

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